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Question
A genetic polymorphism that decreases the activity of N5,N10 methylene tetrahydrofolate reductase has been identified. This would cause _____.a. an accumulation of 5-methyl THF
b. an increase in the homocysteine concentration in the cell
c. a decreased risk for megaloblastic anemia
d. a decreased risk for heart disease
Answer
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Related questions
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Describe the process by which vitamin B12 is digested and absorbed.
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For each vitamin listed below, indicate: (1) the active form of the vitamin, (2) the general function for the vitamin, and (3) an example of the general function (this could be a specific reaction or simply indicate a pathway/ process where it occurs). An example is provided; as you can see, your answers do not need to be long!Vitamins: Biotin, pantothenate, riboflavin, vitamin B6, thiamin, vitamin C, folateExample: Niacin(1) NAD(H) or NADP(H)(2) Oxidation-reduction reactions(3) TCA Cycle reaction or"¦.
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Match the nutrient listed to the phrase or word given. Nutrient choices may be used more than once.Associated Phrase1) hypochromic, microcytic anemia2) serine hydroxymethyltransferase3) edema and cardiac insufficiency4) hemoglobin synthesis5) prolyl hydroxylase6) Latin word means "leaf"; Italian word means "foliage"7) PLP is coenzyme form8) potatoes and broccoli are good sources9) coenzyme carries one-carbon groups in metabolism10) pernicious anemia is a lack of absorption of this11) gulonolactone oxidase12) coenzyme labilizes covalent bonds around the alpha-carbon of an amino acid13) UL = 2000 mg/d14) a water-soluble vitamin that is not a coenzyme15) a vitamin whose supplement form has MORE biologic action than the form found in natureNutrienta. vitamin B12b. vitamin B6c. folate or folic acidd. vitamin Ce. none of these
Q:
Indicate whether the statement is true or false. If the statement is false, explain why it is false.
Circulating concentrations of a vitamin typically reflect diet, whereas intracellular (e.g., RBCs, leukocytes) concentrations reflect body pools.
Q:
Indicate whether the statement is true or false. If the statement is false, explain why it is false.
High circulating levels of homocysteine (i.e., hyperhomocysteinemia) have been implicated in a number of pathologies including cardiovascular disease.
Q:
Which of the following vitamins has a Tolerable Upper Intake Level established?
a. thiamin
b. riboflavin
c. vitamin B6
d. vitamin B12
Q:
The normal digestion and absorption of cobalamin requires adequate protein digestion in the stomach; the presence of 2 nonenzymatic proteins: _____; and a receptor located in the _____.
a. R binders and hydrochloric acid, colon
b. pepsin and hydrochloric acid, ileum
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d. R protein and intrinsic factor, duodenum
Q:
What amount of supplemental folic acid is recommended daily for women of childbearing age in the United States?
a. 200 ug DFE
b. 400 ug DFE
c. 600 ug DFE
d. 800 ug DFE
Q:
Tetrahydrofolate is vitally important for dividing cells during growth and cancer and knowledge of this need is used in cancer treatment by giving the drug methotrexate to inhibit the enzyme _____.
a. folylpolyglutamate synthetase
b. dihydrofolate reductase
c. formimino glutamate
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Q:
Synthesis of coenzyme A starts with the phosphorylation of which vitamin?
a. pyridoxal phosphate
b. pantothenic acid
c. vitamin E
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Q:
Erythrocyte transketolase activity is an assay to assess the status of:
a. thiamin.
b. B6.
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Describe how the effects of anorexia nervosa are similar to the effects of starvation.
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Explain the difference between direct calorimetry and indirect calorimetry.
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a. 127 lb
b. 130 lb
c. 137 lb
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The present diet of the student in question #25 provides 2500 kcal per day. This diet:
a. is meeting her kcal needs.
b. needs to be increased by 300 kcal.
c. would cause about 1 lb per week weight loss.
d. would cause weight gain of about 0.5 lb per week.
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Q:
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a. secure prior approval to sell their products
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c. provide a disclaimer on the label stating that "this statement has not been evaluated by the Food and Drug Administration"
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Explain the physiological role of silicon in normal growth and bone development.
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c. nickel
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Which ultratrace element is not required by humans in its ionic form, but is a necessary component of the coenzyme form of a vitamin?
a. iron
b. boron
c. cobalt
d. vanadium
Q:
Toxicity of which element results in green tongue, diarrhea, and GI cramps?
a. vanadium
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c. arsenic
d. boron
Q:
An ultratrace element that can inhibit many systems that require phosphate, such as phosphotransferases, is _____.
a. nickel
b. arsenic
c. vanadium
d. boron
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Which ultratrace element, in pharmacological quantities, mimics the action of insulin?
a. boron
b. silicon
c. nickel
d. vanadium
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Which ultratrace element affects the composition, structure, and strength of bones as well as cell membrane stability and inflammation?
a. vanadium
b. cobalt
c. arsenic
d. boron
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Which of the following groups of foods are richest in boron, providing 1.0 to 4.5 mg/100 g?
a. raisins, legumes, nuts, and avocados
b. pork, beef, and poultry
c. milk , butter, cheese, and yogurt
d. fish and shellfish
Q:
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a. arsenic
b. vanadium
c. boron
d. silicon
Q:
What two minerals can cause damage to cells when in their free ion forms?
a. iron and copper
b. zinc and molybdenum
c. iodine and manganese
d. zinc and copper
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Which vitamin may enhance copper reduction?a. niacinb. biotinc. ascorbic acidd. -carotene