Question

A number of metabolic pathways have a problem in that certain components required for them to function are found in either the cytosol or the mitochondria, and some intermediates cannot cross the membrane. This requires that certain compounds be shuttled from one compartment to the other. Explain this shuttling process for either: (a) glycolysis/TCA cycle OR (b) gluconeogenesis. Your answer should include: what needs to be shuttled, why it needs to be shuttled, and how this is accomplished.

Answer

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