Question

All are components of the basic rule of macromolecular recognition EXCEPT:
a. protein recognizes nucleotide sequences by atomic contacts with bases and sugar-phosphate backbone usually in the major groove.
b. protein contacts involve H-bonds and salt bridges with electronegative oxygens of the phosphodiester linkages.
c. proteins present a three-dimensional shape or contour structurally and chemically complementary to the surface of the DNA sequence.
d. numerous atomic interactions underlie recognition and binding.
e. all are components.

Answer

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