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Question
All are correct about enhancer sequences in eukaryotic cells EXCEPT:a. they can occur either upstream or downstream of the gene.
b. they can be in either orientation (bi-directional).
c. enhancer function is dependent on recognition by a specific transcription factor.
d. specific transcription factor binding at an enhancer stimulates transcription by interacting with RNA polymerase II.
e. all are correct.
Answer
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Related questions
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In general, proteins whose folding is chaperone-dependent start the folding process first with ____ and then are passed as ____ folded intermediates to ____.
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b. Hsp90; un-; chaperonin
c. Hsp70; partially; chaperonin
d. Hsp40; partially; Hsp70
e. Hsp60; partially; Hsp40
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Which of the following is responsible for Alzheimer's disease?
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d. mutation in the huntingtin gene
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Which of the following correctly describes the order of events in the class I aminoacyl-tRNA synthetase reaction?I. displacement of AMPII. transesterificationIII. nucleophilic attack by 2'-hydroxyl of the tRNA on the acyl adenylateIV. formation of acyl adenylate by reaction of amino acid with ATPV. displacement and subsequent hydrolysis of pyrophosphatea. III, I, IV, V, IIb. III, V, IV, I, IIc. IV, II, I, III, Vd. IV, V, III, I, IIe. IV, I, III, II, V
Q:
In a class I aminoacyl-tRNA synthetase, which of the following reacts with the acyl phosphate formed during the reaction of ATP with the amino acid?a. 5'-hydroxyl of the nucleotide on the 5' end of the tRNA moleculeb. 3'-hydroxyl of the nucleotide on the 5' end of the tRNA moleculec. 2'-hydroxyl of the nucleotide on the 5' end of the tRNA moleculed. 3'-hydroxyl of the nucleotide on the 3' end of the tRNA moleculee. 2'-hydroxyl of the nucleotide on the 3' end of the tRNA molecule
Q:
Each of the following statements regarding ways in which eukaryotic protein synthesis differs from prokaryotic protein synthesis is true EXCEPT:
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b. prokaryotes use a 30S small ribosomal subunit, while eukaryotes use a 40S small ribosomal subunit
c. prokaryotic and eukaryotic translation initiation differ significantly in mechanism and process
d. prokaryotic termination involves three release factors, while eukaryotic termination involves one
e. all of the above are true statements
Q:
Ribosome:mRNA:P-site tRNA complex, with the help of ____, is disassembled by ____ which is an excellent molecular mimic of a(n) ____.
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Q:
Termination of translation in prokaryotic cells requires:
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b. interaction of release factors with the termination codon.
c. ternary interaction of the release factor and the termination tRNA with the termination codon.
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Q:
Which of the following does not reqire GTP hydrolysis?
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b. the binding of the aminoacyl tRNA to the A site during elongation
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Q:
Which of the following statements is true regarding the formylmethionine that serves as the first amino acid in bacterial protein synthesis?
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Q:
Mitochondrial and chloroplastic ribosomes resemble ____ ribosomes.
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c. higher eukaryotic
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Q:
Ribosomal proteins are typically rich in the amino acids ____ and ____ to interact with ____ RNAs.
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b. asp; ala; polycationic
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Q:
Nonsense suppression is the production of isoacceptor tRNAs called ____ tRNAs that read ____ codons and insert an amino acid.
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Q:
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Q:
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Q:
The genetic code is said to be degenerate, which means that:
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d. The code is universally used by virtually all species.
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The linkage between the amino acid and the tRNA in an amino-acyl tRNA complex is:
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Q:
The araBAD operon allows for the use of what metabolite by E. coli?
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Q:
Spliceosomes include all of the following EXCEPT:
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Q:
Transcription of a typical gene encoding a polypeptide in eukaryotes involves all of the following EXCEPT:
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Q:
The base-pair edges in the ____ groove act as a(n) ____ identifiable through ____ with specific proteins.
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Q:
The eukaryotic transcription factor that exhibits a sequence specificity for the TATA box is:
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c. TFIID/TBP.
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Q:
All are characteristics of catabolic activator protein (CAP) EXCEPT:
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e. all are true.
Q:
Characteristics of rho factor include all EXCEPT that it:a. recognizes and binds C-rich regions of RNA transcripts.b. binding regions must be ribosome free.c. advances in the 5'->3' direction to the transcription bubble.d. unwinds transcript and template to free nascent RNA.e. all are true.
Q:
The base in DNA that specifies the first base in the RNA transcript is called a(n) ____ and is numbered ____.a. promoter; -5b. enhancer; -35c. transcription start site; 0d. transcription start site; +1e. promoter complex; +5
Q:
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c. a chemical mutagen such as nitrous acid
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e. none of the above
Q:
Which of the following statements explains why the adenine analog, 2-aminopurine (2-AP), can cause mutations in DNA when it is inserted in place of a site normally occupied by A?
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b. 2-AP undergoes oxidative deaminiation to hypoxanthine which basepairs with C
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d. 2-AP is often found as a schiff base that crosslinks with T
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Q:
Misincorporation of all subsequent amino acids results from ____ mutations.
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Q:
Mutations in DNA may result from all of the following EXCEPT:
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b. physical insults on the cell, such as UV light.
c. errors in transcription.
d. chemical mutagens.
e. introduction of a base analog into DNA.
Q:
A transition mutation would be replacing A by:
a. T.
b. C.
c. U.
d. G.
e. either T or C
Q:
____ promotes the formation of covalent bonds between ____ thymine residues in a DNA strand creating a ____ ring called a thymidine dimer.
a. Visible light; adjacent; cyclohexyl
b. Visible light; nearby; cyclobutyl
c. UV light; adjacent; cyclobutyl
d. UV light; nearby; cyclohexyl
e. IR light; adjacent; cyclobutyl