Question


Following carrier testing, it is determined that both the husband and wife have sickle-cell trait. Which statement by the wife indicates correct understanding of autosomal recessive inheritance?
1. "Because both my husband and I carry the trait but do not have the disease, I don"t need to have prenatal testing because my baby will also be a carrier."
2. "Because both my husband and I are both carriers, I don"t need to have prenatal testing because all of our children will have the disease.
3. "When I become pregnant, I need to have an amniocentesis or other prenatal test to determine whether my baby is affected with sickle-cell disease."
4. "There is no use undergoing prenatal testing as sickle-cell anemia cannot be diagnosed prenatally."

Answer

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