Question

In order for transcription to begin, the DNA-duplex must be "opened" to allow RNA polymerase access to single stranded template. All facilitate "opening" of DNA-duplex EXCEPT:
a. low melting temperature, Tm, in the Pribnow box.
b. A:T rich DNA duplex.
c. negative supercoiling.
d. binding of RNA polymerase -subunit.
e. all are true.

Answer

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