Question

Isocitrate dehydrogenase has all of the characteristics EXCEPT:
a. ADP raises the Km for isocitrate by a factor of 10.
b. virtually inactive in the absence of ADP.
c. sufficiently exergonic to pull the aconitase reaction forward.
d. allosterically inhibited by NADH and ATP.
e. an oxidative-decarboxylation reaction.

Answer

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