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Question
The client with schizophrenia was started on imipramine (Tofranil) for a depressed mood and subsequently started hearing voices again and refuses to take the Tofranil because the client thinks it is poison. The nursing response is based on what information?1. Tricyclic antidepressants can trigger overt symptoms in someone with schizophrenia.
2. There is no evidence that tricyclic antidepressants trigger psychotic symptoms in susceptible clients.
3. Often new antipsychotic medications like imipramine have paradoxical effects.
4. MAOIs do not interact well with other antipsychotic medications and can cause worsening of symptoms.
Answer
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