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Question
Thymine nucleotides are not synthesized directly by cells but indirectly from other pyrimidine deoxyribonucleotides. All of the following statements regarding thymine nucleotide synthesis are true EXCEPT:a. dUMP is the immediate precursor for dTMP.
b. The action of dUTPase allows dUTP to serve as a substrate in DNA synthesis.
c. Thymidylate synthase catalyzes the formation of dTMP from dUMP.
d. The methyl donor in the reaction of dTMP is N5, N10-methylene-THF.
e. THF is used as a cofactor.
Answer
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