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Question
Urea and formamide are agents that denature dsDNA bya. intercalating between base pairs and disrupting van der Waals interactions.
b. forming ionic bonds with the backbone phosphates.
c. competing effectively with the H-bonding between the base pairs.
d. changing the pH to cause hydrolysis.
e. none are true
Answer
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Related questions
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In general, proteins whose folding is chaperone-dependent start the folding process first with ____ and then are passed as ____ folded intermediates to ____.
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b. Hsp90; un-; chaperonin
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d. Hsp40; partially; Hsp70
e. Hsp60; partially; Hsp40
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Q:
In a class I aminoacyl-tRNA synthetase, which of the following reacts with the acyl phosphate formed during the reaction of ATP with the amino acid?a. 5'-hydroxyl of the nucleotide on the 5' end of the tRNA moleculeb. 3'-hydroxyl of the nucleotide on the 5' end of the tRNA moleculec. 2'-hydroxyl of the nucleotide on the 5' end of the tRNA moleculed. 3'-hydroxyl of the nucleotide on the 3' end of the tRNA moleculee. 2'-hydroxyl of the nucleotide on the 3' end of the tRNA molecule
Q:
Each of the following statements regarding ways in which eukaryotic protein synthesis differs from prokaryotic protein synthesis is true EXCEPT:
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d. prokaryotic termination involves three release factors, while eukaryotic termination involves one
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Q:
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Q:
Termination of translation in prokaryotic cells requires:
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b. interaction of release factors with the termination codon.
c. ternary interaction of the release factor and the termination tRNA with the termination codon.
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Q:
Which of the following does not reqire GTP hydrolysis?
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b. the binding of the aminoacyl tRNA to the A site during elongation
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Q:
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Q:
Mitochondrial and chloroplastic ribosomes resemble ____ ribosomes.
a. prokaryotic
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c. higher eukaryotic
d. no other
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Q:
Ribosomal proteins are typically rich in the amino acids ____ and ____ to interact with ____ RNAs.
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b. asp; ala; polycationic
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d. ala; arg; polyanionic
e. arg; lys; polyanionic
Q:
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Q:
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Q:
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Q:
The genetic code is said to be degenerate, which means that:
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d. The code is universally used by virtually all species.
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Q:
The linkage between the amino acid and the tRNA in an amino-acyl tRNA complex is:
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Q:
The araBAD operon allows for the use of what metabolite by E. coli?
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c. allose
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Q:
Spliceosomes include all of the following EXCEPT:
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Q:
Transcription of a typical gene encoding a polypeptide in eukaryotes involves all of the following EXCEPT:
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Q:
The base-pair edges in the ____ groove act as a(n) ____ identifiable through ____ with specific proteins.
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Q:
The eukaryotic transcription factor that exhibits a sequence specificity for the TATA box is:
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c. TFIID/TBP.
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Q:
All are correct about enhancer sequences in eukaryotic cells EXCEPT:
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Q:
All are characteristics of catabolic activator protein (CAP) EXCEPT:
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e. all are true.
Q:
Characteristics of rho factor include all EXCEPT that it:a. recognizes and binds C-rich regions of RNA transcripts.b. binding regions must be ribosome free.c. advances in the 5'->3' direction to the transcription bubble.d. unwinds transcript and template to free nascent RNA.e. all are true.
Q:
The base in DNA that specifies the first base in the RNA transcript is called a(n) ____ and is numbered ____.a. promoter; -5b. enhancer; -35c. transcription start site; 0d. transcription start site; +1e. promoter complex; +5
Q:
Which of the following would most likely cause a frameshift mutation?
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b. a base analog such as 5-bromouracil
c. a chemical mutagen such as nitrous acid
d. an intercalation agent such as acridine orange
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Q:
Which of the following statements explains why the adenine analog, 2-aminopurine (2-AP), can cause mutations in DNA when it is inserted in place of a site normally occupied by A?
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b. 2-AP undergoes oxidative deaminiation to hypoxanthine which basepairs with C
c. 2-AP can form a single hydrogen bond with C
d. 2-AP is often found as a schiff base that crosslinks with T
e. none of the above
Q:
Misincorporation of all subsequent amino acids results from ____ mutations.
a. chemical
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Q:
Mutations in DNA may result from all of the following EXCEPT:
a. spontaneous mutations due to errors in replication.
b. physical insults on the cell, such as UV light.
c. errors in transcription.
d. chemical mutagens.
e. introduction of a base analog into DNA.
Q:
A transition mutation would be replacing A by:
a. T.
b. C.
c. U.
d. G.
e. either T or C