Question

Which of the following weak acids would make the best buffer at pH = 5.0?
a. acetic acid (Ka = 1.74 x 10-5, pKa = 4.76)
b. H2PO4- (Ka = 1.38 x 10-7, pKa = 7.20)
c. bicarbonate (Ka = 6.3 x 10-11, pKa = 10.24)
d. tris-hydroxymethyl aminomethane (Ka = 8.32 x 10-9, pKa = 8.07)
e. lactic acid (Ka = 1.38 x 10-4, pKa = 3.86)

Answer

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